hermes erenumab | Erenumab versus topiramate for the prevention of migraine – a hermes erenumab Background: We compared the tolerability and efficacy of erenumab, a monoclonal antibody binding to the calcitonin gene-related peptide receptor, to topiramate for migraine prophylaxis . $590.00
0 · Pharmacologic prevention of migraine
1 · Novartis announces positive results from a Phase IV study
2 · Medium
3 · Long
4 · HER
5 · Erenumab versus topiramate: post hoc efficacy analysis from the
6 · Erenumab versus topiramate: post hoc efficacy analysis from
7 · Erenumab versus topiramate for the prevention of migraine – a
8 · Erenumab versus topiramate for the prevention of migraine
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Pharmacologic prevention of migraine
Background: We compared the tolerability and efficacy of erenumab, a monoclonal antibody binding to the calcitonin gene-related peptide receptor, to topiramate for migraine prophylaxis .Basel, November 2, 2020 — Novartis announced today that HER-MES, the first Phase IV, randomized, double-blind, double-dummy, head-to-head study of Aimovig ® (erenumab) .
In 2022, a trial (Head-to-Head Study of Erenumab Against Topiramate in Patients with Episodic and Chronic Migraine [HERMES]) comparing erenumab and topiramate for the prevention of .
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Objective: HER-MES was the first head-to-head, phase 4 trial to assess the tolerability and effectiveness of erenumab against standard of care treatment (topiramate). .HER-MES is the first randomized, double blind, head-to-head study of Aimovig® (erenumab) against topiramate in patients with episodic and chronic migraine1. KEY CLINICAL TRIAL . Although some open label extension studies have become available for erenumab, there is a lack of real-world data pertaining to quality of life in the medium to long-term for . HER-MES (Head-to-head study of erenumab against topiramate – Migraine study to assess tolerability and efficacy in a patient-centred setting) aimed to directly compare the .
Uwe Reuter, MD, PhD, MBA, Charité – University Medicine Berlin, Berlin, Germany, outlines the characteristics of the HER-MES study (NCT03828539), the first head-to .Patients initially received open-label erenumab 70 mg, which increased to 140 mg following a protocol amendment. Efficacy analyses included change from baseline in monthly migraine .
Background: We compared the tolerability and efficacy of erenumab, a monoclonal antibody binding to the calcitonin gene-related peptide receptor, to topiramate for migraine prophylaxis in adults. Methods: HER-MES was a 24-week, randomised, double-blind, double-dummy, controlled trial conducted in 82 sites in Germany.Basel, November 2, 2020 — Novartis announced today that HER-MES, the first Phase IV, randomized, double-blind, double-dummy, head-to-head study of Aimovig ® (erenumab) against topiramate, an anticonvulsant, in patients with episodic and chronic migraine met its primary and secondary endpoints.
In 2022, a trial (Head-to-Head Study of Erenumab Against Topiramate in Patients with Episodic and Chronic Migraine [HERMES]) comparing erenumab and topiramate for the prevention of migraine was published. 38 The HER-MES study was a 24-week, randomized, double-blind, placebo-controlled trial conducted in adults (n = 777); most patients had . HER-MES was the first head-to-head, phase 4 trial to assess the tolerability and effectiveness of erenumab against standard of care treatment (topiramate). This post hoc analysis compared the efficacy of erenumab with topiramate in . Objective: HER-MES was the first head-to-head, phase 4 trial to assess the tolerability and effectiveness of erenumab against standard of care treatment (topiramate). This post hoc analysis compared the efficacy of erenumab with topiramate in patients who completed the trial on study medication.HER-MES is the first randomized, double blind, head-to-head study of Aimovig® (erenumab) against topiramate in patients with episodic and chronic migraine1. KEY CLINICAL TRIAL DETAILS. Patients: Endpoints. Dose:
Although some open label extension studies have become available for erenumab, there is a lack of real-world data pertaining to quality of life in the medium to long-term for chronic and treatment resistant migraine patients. HER-MES (Head-to-head study of erenumab against topiramate – Migraine study to assess tolerability and efficacy in a patient-centred setting) aimed to directly compare the tolerability and efficacy of the CGRP receptor antibody erenumab to topiramate.
Uwe Reuter, MD, PhD, MBA, Charité – University Medicine Berlin, Berlin, Germany, outlines the characteristics of the HER-MES study (NCT03828539), the first head-to-head randomized, double-blind, double-dummy trial of erenumab and topiramate for the prevention of episodic and chronic migraine.
Patients initially received open-label erenumab 70 mg, which increased to 140 mg following a protocol amendment. Efficacy analyses included change from baseline in monthly migraine days (MMDs), monthly acute migraine-specific medication .
Background: We compared the tolerability and efficacy of erenumab, a monoclonal antibody binding to the calcitonin gene-related peptide receptor, to topiramate for migraine prophylaxis in adults. Methods: HER-MES was a 24-week, randomised, double-blind, double-dummy, controlled trial conducted in 82 sites in Germany.Basel, November 2, 2020 — Novartis announced today that HER-MES, the first Phase IV, randomized, double-blind, double-dummy, head-to-head study of Aimovig ® (erenumab) against topiramate, an anticonvulsant, in patients with episodic and chronic migraine met its primary and secondary endpoints.In 2022, a trial (Head-to-Head Study of Erenumab Against Topiramate in Patients with Episodic and Chronic Migraine [HERMES]) comparing erenumab and topiramate for the prevention of migraine was published. 38 The HER-MES study was a 24-week, randomized, double-blind, placebo-controlled trial conducted in adults (n = 777); most patients had . HER-MES was the first head-to-head, phase 4 trial to assess the tolerability and effectiveness of erenumab against standard of care treatment (topiramate). This post hoc analysis compared the efficacy of erenumab with topiramate in .
Objective: HER-MES was the first head-to-head, phase 4 trial to assess the tolerability and effectiveness of erenumab against standard of care treatment (topiramate). This post hoc analysis compared the efficacy of erenumab with topiramate in patients who completed the trial on study medication.HER-MES is the first randomized, double blind, head-to-head study of Aimovig® (erenumab) against topiramate in patients with episodic and chronic migraine1. KEY CLINICAL TRIAL DETAILS. Patients: Endpoints. Dose: Although some open label extension studies have become available for erenumab, there is a lack of real-world data pertaining to quality of life in the medium to long-term for chronic and treatment resistant migraine patients.
HER-MES (Head-to-head study of erenumab against topiramate – Migraine study to assess tolerability and efficacy in a patient-centred setting) aimed to directly compare the tolerability and efficacy of the CGRP receptor antibody erenumab to topiramate. Uwe Reuter, MD, PhD, MBA, Charité – University Medicine Berlin, Berlin, Germany, outlines the characteristics of the HER-MES study (NCT03828539), the first head-to-head randomized, double-blind, double-dummy trial of erenumab and topiramate for the prevention of episodic and chronic migraine.
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hermes erenumab|Erenumab versus topiramate for the prevention of migraine – a